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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) |
| Enrichment Score (ES) | -0.81215936 |
| Normalized Enrichment Score (NES) | -1.7783654 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006710742 |
| FWER p-Value | 0.0060 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPK8 | 6459 | 2014 | 1.381 | -0.0881 | No | ||
| 2 | MAP2K1 | 19082 | 2547 | 0.862 | -0.1040 | No | ||
| 3 | MAP2K2 | 19933 | 3294 | 0.375 | -0.1387 | No | ||
| 4 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 3317 | 0.365 | -0.1345 | No | ||
| 5 | AKT1 | 8568 | 4184 | 0.164 | -0.1787 | No | ||
| 6 | KIT | 16823 | 4387 | 0.142 | -0.1875 | No | ||
| 7 | SPRED2 | 8539 4332 | 4420 | 0.139 | -0.1872 | No | ||
| 8 | SHC1 | 9813 9812 5430 | 4421 | 0.139 | -0.1851 | No | ||
| 9 | STAT5A | 20664 | 4510 | 0.131 | -0.1879 | No | ||
| 10 | HRAS | 4868 | 4707 | 0.115 | -0.1968 | No | ||
| 11 | PTPRO | 1093 17256 | 4734 | 0.113 | -0.1965 | No | ||
| 12 | MATK | 3425 19930 | 5418 | 0.076 | -0.2322 | No | ||
| 13 | SNAI2 | 22848 | 6671 | 0.041 | -0.2990 | No | ||
| 14 | GRB10 | 4799 | 6977 | 0.035 | -0.3149 | No | ||
| 15 | EPO | 8911 | 6998 | 0.035 | -0.3155 | No | ||
| 16 | GRAP2 | 5113 9398 | 7076 | 0.033 | -0.3191 | No | ||
| 17 | LYN | 16281 | 9750 | -0.003 | -0.4630 | No | ||
| 18 | KITLG | 19889 3342 | 10459 | -0.012 | -0.5010 | No | ||
| 19 | DOK1 | 17104 1018 1177 | 10626 | -0.015 | -0.5097 | No | ||
| 20 | SOS1 | 5476 | 10751 | -0.016 | -0.5161 | No | ||
| 21 | PIK3R1 | 3170 | 11694 | -0.031 | -0.5664 | No | ||
| 22 | MITF | 17349 | 11768 | -0.032 | -0.5699 | No | ||
| 23 | CBL | 19154 | 11843 | -0.033 | -0.5734 | No | ||
| 24 | PTPN11 | 5326 16391 9660 | 12087 | -0.038 | -0.5859 | No | ||
| 25 | FOXO3 | 19782 3402 | 13431 | -0.077 | -0.6571 | No | ||
| 26 | EPOR | 19204 | 13643 | -0.088 | -0.6671 | No | ||
| 27 | PIK3CA | 9562 | 13936 | -0.107 | -0.6813 | No | ||
| 28 | JAK2 | 23893 9197 3706 | 14343 | -0.140 | -0.7011 | No | ||
| 29 | SPRED1 | 4331 | 14947 | -0.225 | -0.7302 | No | ||
| 30 | RPS6KB1 | 7815 1207 13040 | 15117 | -0.261 | -0.7355 | No | ||
| 31 | SH2B3 | 5001 16383 | 15271 | -0.301 | -0.7393 | No | ||
| 32 | RAF1 | 17035 | 16625 | -1.259 | -0.7936 | Yes | ||
| 33 | MAPK3 | 6458 11170 | 16645 | -1.295 | -0.7755 | Yes | ||
| 34 | MAP4K1 | 18313 | 16826 | -1.546 | -0.7624 | Yes | ||
| 35 | TEC | 16514 | 16891 | -1.651 | -0.7415 | Yes | ||
| 36 | GRB2 | 20149 | 17099 | -1.953 | -0.7239 | Yes | ||
| 37 | CREBBP | 22682 8783 | 17516 | -2.659 | -0.7071 | Yes | ||
| 38 | BAD | 24000 | 17607 | -2.854 | -0.6699 | Yes | ||
| 39 | GSK3B | 22761 | 17749 | -3.186 | -0.6306 | Yes | ||
| 40 | CRKL | 4560 | 17866 | -3.568 | -0.5842 | Yes | ||
| 41 | SOCS1 | 4522 | 17909 | -3.698 | -0.5320 | Yes | ||
| 42 | VAV1 | 23173 | 18053 | -4.129 | -0.4788 | Yes | ||
| 43 | PTEN | 5305 | 18232 | -5.045 | -0.4141 | Yes | ||
| 44 | PDPK1 | 23097 | 18270 | -5.228 | -0.3390 | Yes | ||
| 45 | GAB1 | 18828 | 18330 | -5.503 | -0.2611 | Yes | ||
| 46 | STAT1 | 3936 5524 | 18359 | -5.675 | -0.1790 | Yes | ||
| 47 | STAT3 | 5525 9906 | 18377 | -5.818 | -0.0941 | Yes | ||
| 48 | PTPN6 | 17002 | 18509 | -7.257 | 0.0058 | Yes |
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